N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
Palonosetron Intermediate
CAS: 135729-78-1
Molecular Formula: C18H24N2O
N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide - Names and Identifiers
N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide - Physico-chemical Properties
| Molecular Formula | C18H24N2O |
| Molar Mass | 284.4 |
| Density | 1.17 |
| Melting Point | 157-159oC |
| Boling Point | 439.2°C at 760 mmHg |
| Flash Point | 219.4°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 6.48E-08mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| Storage Condition | Refrigerator |
| Refractive Index | 1.609 |
| Use | Intermediate |
N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide - Introduction
Palonosetron hydrochloride intermediate is a chemical substance whose chemical name is 1-methyl -4-aryl -4-butene -1-amine hydrochloride. The following is a description of its nature, use, preparation and safety information:
Nature:
-Palonosetron hydrochloride intermediate is a colorless to light yellow solid with a special smell.
-It is soluble in water at room temperature, but has low solubility in organic solvents.
-It is a strong organic base with a pKa value of about 7-8.
Use:
-Palonosetron hydrochloride intermediates are widely used in the synthesis of various drugs and intermediates in pharmaceutical chemistry.
-It can be used as a key raw material for the synthesis of antiepileptic drugs, anticancer drugs, antidepressants, etc.
-In addition, it can also be used for the synthesis of dyes and dye intermediates.
Preparation Method:
-palonosetron hydrochloride intermediates are generally prepared by chemical synthesis.
-The specific synthesis route and reaction conditions can be determined according to specific needs, and usually involve the use of corresponding organic synthesis reagents and reaction conditions.
Safety Information:
-Palonosetron hydrochloride intermediate is an organic compound, and attention should be paid to its safe use.
-Wear appropriate personal protective equipment such as gloves, glasses and lab coats during operation.
-Avoid contact with skin, eyes and respiratory tract. If splashed, rinse immediately with plenty of water.
-In the process of storage and handling, should avoid contact with oxidants and strong acids and bases and other substances that are prone to reaction.
-It is recommended to operate in a professional laboratory environment and operate in accordance with relevant safety standards and operating procedures.
Nature:
-Palonosetron hydrochloride intermediate is a colorless to light yellow solid with a special smell.
-It is soluble in water at room temperature, but has low solubility in organic solvents.
-It is a strong organic base with a pKa value of about 7-8.
Use:
-Palonosetron hydrochloride intermediates are widely used in the synthesis of various drugs and intermediates in pharmaceutical chemistry.
-It can be used as a key raw material for the synthesis of antiepileptic drugs, anticancer drugs, antidepressants, etc.
-In addition, it can also be used for the synthesis of dyes and dye intermediates.
Preparation Method:
-palonosetron hydrochloride intermediates are generally prepared by chemical synthesis.
-The specific synthesis route and reaction conditions can be determined according to specific needs, and usually involve the use of corresponding organic synthesis reagents and reaction conditions.
Safety Information:
-Palonosetron hydrochloride intermediate is an organic compound, and attention should be paid to its safe use.
-Wear appropriate personal protective equipment such as gloves, glasses and lab coats during operation.
-Avoid contact with skin, eyes and respiratory tract. If splashed, rinse immediately with plenty of water.
-In the process of storage and handling, should avoid contact with oxidants and strong acids and bases and other substances that are prone to reaction.
-It is recommended to operate in a professional laboratory environment and operate in accordance with relevant safety standards and operating procedures.
Last Update：2024-04-09 20:52:54
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Spot supply
Product Name: Palonosetron Impurity 25 Visit Supplier Webpage Request for quotationCAS: 135729-78-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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